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            暖通空調雜志社>期刊目次>2021年>第7期

            屏障環境下換籠操作對局部潔凈度影響的動態研究

            Dynamic study on effect of cage changing operation on local cleanliness in barrier environment

            Zhang Jianping and Fu Jiangnan
            暨南大學實驗動物管理中心

            摘要:

            由于屏障環境潔凈度參數在GB 14925—2010《實驗動物  環境及設施》中是靜態指標,為了探索屏障環境內動物飼育區動態空氣潔凈度變化規律及屏障環境污染原因,為作業指導書提出理論依據,故進行本實驗研究。采用在線空氣粒子計數器,對獨立通風籠盒系統不同操作空間進行了潔凈度評價和統計分析。結果顯示,因換籠操作引發動物飼養室內發塵量劇增,潔凈度降低。實踐中,現行國家標準對運行狀態下屏障環境內潔凈度無具體要求,由于忽略潔凈室產塵量少的基本原則,導致發塵量大增,潔凈度降低。

            關鍵詞:屏障環境,潔凈度,換籠操作,實驗動物,粒子濃度

            Abstract:

            Since the cleanliness parameter of the barrier environment is a static index in the GB 14925-2010 Laboratry animal—Requirements of environment and housing facilities, carries out the experimental study in order to explore the dynamic air cleanliness changes in animal feeding areas in the barrier environment and the reasons for the barrier environment pollution, and to provide a theoretical basis for the operating instructions. Using the online air particle counter, evaluates and statistically analyses the cleanliness of different operating spaces of the independent ventilation cage system. The results show that due to the cage changing operation, the amount of dust in the animal feeding room will increase sharply, and the cleanliness level will reduce. In practice, the current national standards have no specific requirements for the cleanliness of the barrier environment under operating conditions. Due to the neglect of the basic principle of low dust production in clean rooms, the amount of dust is greatly increased and the cleanliness is reduced.

            Keywords:barrierenvironment,cleanliness,cagechangingoperation,laboratoryanimal,particleconcentration

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